Long-term results of liver-first approach strategy in patients with advanced synchronous liver metastases from colorectal cancer.

Eric Herrero, María Galofré, Alba Zárate, Maribel García-Domingo, Judith Camps, Fernando Pardo, Francisco Espin y Esteban Cugat.

Retrospective descriptive analysis from a prospective database of hepatectomies from liver metastases (LM) from CRC in two centers. Between 2007-2019, 88 patients with CRC-ASLM (advanced synchronous liver metastases) were included in a LFA scheme. Bilobar (LM) was present in 65.9%, the mean number of lesions was 5.5 and mean size 42.7 mm. Response to treatment was assessed by RECIST criteria. Progression-free survival (PFS) and overall survival (OS) were estimated using Kaplan-Meier survival curves.

In patients with CRC-ASLM the LFA allows control of the liver disease beforehand and an assessment of the tumor response to neoadjuvant chemotherapy, optimising the chance of potentially curative liver resection, which influences long-term survival.

Doctors who have participated

Dra. Zárate

Consultant in Hepatobiliopancreatic Surgery

Dr. Alba Zárate (Barcelona, 1989) is a Digestive surgeon specializing in hepatobiliopancreatic surgery and pancreatic transplantation.

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Dr. Cugat

Clinical Head of the Hepatobiliopancreatic Surgery Team

Dr. Esteban Cugat (Barcelona, 1960) is a medical specialist in General and Digestive System Surgery. Specialized in Hepatobiliopancreatic Surgery. Clinical Associate Professor at the Faculty of Medicine of the Autonomous University of Barcelona. 

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Dr. Pardo

Consultant in Hepatobiliopancreatic Surgery

Dr. Fernando Pardo (Madrid, 1986) is a Digestive surgeon specializing in hepatobiliopancreatic surgery and pancreatic transplantation.

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Dr. Espín

Consultant in Hepatobiliopancreatic Surgery

Dr. Francisco Espín is a  Medical specialist in hepatobiliopancreatic (HPB) surgery and pancreatic transplantation. Associate Professor at the Faculty of Medicine at the Autonomous University of Barcelona (Germans Trias Teaching Unit).

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